{"id":28113,"date":"2021-11-26T08:33:00","date_gmt":"2021-11-26T08:33:00","guid":{"rendered":"https:\/\/haberglobal.com.tr\/gundem\/prof-dr-mehmet-ceyhandan-yeni-koronavirus-ilaci-molnupiravir-icin-uyari-145836"},"modified":"2021-11-26T08:33:00","modified_gmt":"2021-11-26T08:33:00","slug":"prof-dr-mehmet-ceyhandan-yeni-koronavirus-ilaci-molnupiravir-icin-uyari","status":"publish","type":"post","link":"https:\/\/istanbulchannel.net\/index.php\/2021\/11\/26\/prof-dr-mehmet-ceyhandan-yeni-koronavirus-ilaci-molnupiravir-icin-uyari\/","title":{"rendered":"Prof. Dr. Mehmet Ceyhan’dan yeni koronavir\u00fcs ilac\u0131 molnupiravir i\u00e7in uyar\u0131"},"content":{"rendered":"

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Yay\u0131nlanma: <\/span>

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Hacettepe \u00dcniversitesi T\u0131p Fak\u00fcltesi \u00c7ocuk Enfeksiyon Hastal\u0131klar\u0131 Bilim Dal\u0131 Ba\u015fkan\u0131 Prof. Dr. Mehmet Ceyhan, T\u00fcrkiye’de Covid-19 hastal\u0131\u011f\u0131na kar\u015f\u0131 tedavi rehberine eklenecek ‘Molnupiravir’ ilac\u0131n\u0131n hen\u00fcz Faz-3 \u00e7al\u0131\u015fmas\u0131n\u0131n tamamlanmad\u0131\u011f\u0131n\u0131 s\u00f6yledi. Ceyhan, “Firma Faz-3 \u00e7al\u0131\u015fmas\u0131ndaki ara sonu\u00e7lar ile acil kullan\u0131m onay\u0131 ald\u0131 dolay\u0131s\u0131yla \u2018Molnupiravir\u2019in hen\u00fcz ne oranda etkili oldu\u011funa dair kesin veri yok. Ara sonu\u00e7lar hep yan\u0131ltabilir insanlar\u0131. Bence bu ilac\u0131n etkinli\u011fi ile ilgili Faz-3 \u00e7al\u0131\u015fmas\u0131n\u0131n b\u00fct\u00fcn sonu\u00e7lar\u0131n\u0131 beklemek laz\u0131m” dedi.<\/p>\n

Sa\u011fl\u0131k Bakan\u0131 Fahrettin Koca, Bilim Kurulu Toplant\u0131s\u0131’n\u0131n ard\u0131ndan ‘Favipiravir’ ve ‘Molnupiravir’ ila\u00e7lar\u0131n\u0131n kullan\u0131m\u0131yla ilgili yeni d\u00fczenlemenin rehbere eklenece\u011fini duyurdu. Prof. Dr. Mehmet Ceyhan, \u2018Favipiravir\u2019in Japonlar\u0131n 2014 y\u0131l\u0131nda grip i\u00e7in geli\u015ftirdi\u011fi bir ila\u00e7 oldu\u011funu belirterek, “Arka arkaya yap\u0131lan geni\u015f \u00e7apl\u0131 \u00e7al\u0131\u015fmalarda hi\u00e7bir etkisinin olmad\u0131\u011f\u0131 g\u00f6r\u00fcld\u00fc. Ama \u00f6yle \u00e7al\u0131\u015fmalar ile etkin oldu\u011funa karar verildi ki \u00f6rne\u011fin; 40 ki\u015fide yap\u0131lan \u00e7al\u0131\u015fmalar ile. En son T\u00fcrkiye’de \u00e7ok merkezli \u00e7al\u0131\u015fma yap\u0131ld\u0131 g\u00f6r\u00fcld\u00fc ki \u2018Favipiravir\u2019 ne hastaneye yat\u0131\u015f s\u0131kl\u0131\u011f\u0131n\u0131 ne yo\u011fun bak\u0131ma yat\u0131\u015f s\u0131kl\u0131\u011f\u0131n\u0131 ne de \u00f6l\u00fcm oran\u0131n\u0131 de\u011fi\u015ftiren bir ila\u00e7 de\u011fil. Dolay\u0131s\u0131yla geldi\u011fimiz noktada \u2018Favipiravir\u2019 ve kullan\u0131lan bir\u00e7ok di\u011fer ila\u00e7 da hen\u00fcz koronavir\u00fcse kar\u015f\u0131 etkinli\u011fi g\u00f6sterilmi\u015f ila\u00e7lar de\u011fil. Biz de bu nedenle Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131’n\u0131n rehberinde olmas\u0131na ra\u011fmen salg\u0131n\u0131n ba\u015f\u0131ndan beri \u00e7ocuklara hi\u00e7 kullanmad\u0131k. Hen\u00fcz mevcut kullan\u0131lan, kullan\u0131mda olan koronavir\u00fcse kar\u015f\u0131 etkili bir vir\u00fcs \u00f6ld\u00fcr\u00fcc\u00fc ila\u00e7 yok” diye konu\u015ftu.<\/p>\n

“\u0130LA\u00c7 ARTIK HERKESE VER\u0130LMEYECEK”<\/strong><\/h2>\n

Prof. Dr. Ceyhan, \u2018Favipiravir\u2019in kullan\u0131lmas\u0131na gerek olmad\u0131\u011f\u0131n\u0131 belirterek, “A\u00e7\u0131klama \u015funu g\u00f6steriyor; art\u0131k herkese bu ila\u00e7 verilmeyecek. Ancak doktorun gerekli g\u00f6rd\u00fc\u011f\u00fc hastalara verilecek. Ama doktorun da neye g\u00f6re gerek g\u00f6rece\u011fine dair bir rehber, veri yok. Benim oradan \u00e7\u0131kard\u0131\u011f\u0131m sonu\u00e7; isteyen kullanabilir; ama genel anlamda herkese ‘kullan\u0131n’ \u00f6nerisi yok” dedi.<\/p>\n

“Y\u0130NE ACELE ED\u0130YORUZ”<\/strong><\/h2>\n

Prof. Dr. Ceyhan, \u2018Molnupiravir\u2019 ilac\u0131n\u0131n tedavi rehberine eklenmesi karar\u0131n\u0131n da yine acele al\u0131nm\u0131\u015f bir karar oldu\u011funu savunarak, \u015funlar\u0131 kaydetti:<\/p>\n

“\u2019Molnupiravir\u2019in hen\u00fcz Faz-3 \u00e7al\u0131\u015fmas\u0131 bitmedi. Sadece firma Faz-3 \u00e7al\u0131\u015fmas\u0131ndaki ara sonu\u00e7lar ile acil kullan\u0131m onay\u0131 ald\u0131. Daha sonra da hemen arkas\u0131ndan bir ba\u015fka firman\u0131n daha etkili ilac\u0131 duyuruldu. Bunlardan hi\u00e7birinin bilimsel verisi yay\u0131mlanm\u0131\u015f de\u011fil. ‘Molnupiravir\u2019 \u00f6zellikle hastaneye yat\u0131\u015flar\u0131 y\u00fczde 50 azalt\u0131yor, diye duyuruldu. Halbuki di\u011fer ila\u00e7 y\u00fczde 80’in \u00fczerinde bir etkinlik oldu\u011fundan bahsetti. B\u00f6yle olunca \u2018Molnupiravir\u2019in pazarda yer alma \u015fans\u0131 azald\u0131. Asl\u0131nda bir firman\u0131n bir ila\u00e7 geli\u015ftirdikten sonra 10 y\u0131ll\u0131k veri koruma hakk\u0131 vard\u0131r. Yani verisini kimse ile payla\u015fmama, dolay\u0131s\u0131yla ba\u015fkalar\u0131 taraf\u0131ndan \u00fcretimini engelleme hakk\u0131 vard\u0131r. Firma ba\u015fta kendi a\u00e7\u0131klama yapt\u0131, ‘Ben ruhsat i\u00e7in ba\u015fvurmayaca\u011f\u0131m; ancak \u00fclkeler kendileri bunu kendi imkanlar\u0131 ile \u00fcretebileceklerini d\u00fc\u015f\u00fcn\u00fcyorlarsa onlar i\u00e7in verilerimi verece\u011fim’ dedi. O arada Hindistan’da 7 ayr\u0131 firma \u00fcretimine ba\u015flad\u0131. Bunlardan 2’si Faz-3 \u00e7al\u0131\u015fmas\u0131 yapt\u0131, \u00e7al\u0131\u015fmada orta a\u011f\u0131rl\u0131ktaki vakalara kulland\u0131klar\u0131nda etkisi olmad\u0131\u011f\u0131n\u0131 g\u00f6rd\u00fckleri i\u00e7in \u00e7al\u0131\u015fmay\u0131 sonland\u0131rd\u0131lar.”<\/p>\n

“ARA SONU\u00c7LAR YANILTAB\u0130L\u0130R”<\/strong><\/h2>\n

Prof. Dr. Ceyhan, ilac\u0131n etkinli\u011fine dair kesin veri olmad\u0131\u011f\u0131n\u0131 kaydederek, “Dolay\u0131s\u0131yla \u2018Molnupiravir\u2019in hen\u00fcz ne oranda etkili oldu\u011funa dair kesin veri yok. Ara sonu\u00e7lar hep yan\u0131ltabilir insanlar\u0131. Burada 2 bin civar\u0131nda elde edilen sonu\u00e7 ile var\u0131lm\u0131\u015f bir sonu\u00e7 var, bu da a\u00e7\u0131k\u00e7as\u0131 yan\u0131ltabilir insan\u0131. Ayn\u0131 \u2018Favipiravir\u2019de oldu\u011fu gibi burada da benzer bir durum ile kar\u015f\u0131la\u015fabiliriz. \u00dcretim hakk\u0131n\u0131 firma b\u00fct\u00fcn d\u00fcnyaya a\u00e7t\u0131. Anlad\u0131\u011f\u0131n\u0131z kadar\u0131yla T\u00fcrkiye’de de b\u00f6yle bir ba\u015fvuru yap\u0131lm\u0131\u015f. Bence bu ilac\u0131n etkinli\u011fi ile ilgili verileri \u00f6zellikle Faz-3 \u00e7al\u0131\u015fmas\u0131n\u0131n b\u00fct\u00fcn sonu\u00e7lar\u0131n\u0131 beklemek laz\u0131m. Daha sonra di\u011fer \u00fclkelerde kullan\u0131ma girecek, onlar\u0131n sonu\u00e7lar\u0131n\u0131 g\u00f6rmek laz\u0131m. \u015eimdiden sanki ‘\u00e7aresi bulundu’ diye bir d\u00fc\u015f\u00fcnceye kap\u0131lmak yanl\u0131\u015f olur” diye konu\u015ftu.<\/p>\n

Kaynak: DHA<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

Hacettepe \u00dcniversitesi T\u0131p Fak\u00fcltesi \u00c7ocuk Enfeksiyon Hastal\u0131klar\u0131 Bilim Dal\u0131 Ba\u015fkan\u0131 Prof. Dr. Mehmet Ceyhan, T\u00fcrkiye’de Covid-19 hastal\u0131\u011f\u0131na kar\u015f\u0131 tedavi rehberine…<\/p>\n","protected":false},"author":2,"featured_media":28114,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,185],"tags":[],"class_list":["post-28113","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gundem","category-manset"],"_links":{"self":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts\/28113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/comments?post=28113"}],"version-history":[{"count":0,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts\/28113\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/media\/28114"}],"wp:attachment":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/media?parent=28113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/categories?post=28113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/tags?post=28113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}