ABD<\/a> Ulusal Sa\u011fl\u0131k Enstit\u00fcleri’nin hastanesine kald\u0131r\u0131ld\u0131\u011f\u0131 bildirildi. Covid te\u015fhisi konan hastan\u0131n durumu 335 g\u00fcn pozitif kald\u0131 ve evde oksijen deste\u011fi almas\u0131na neden olan semptomlar\u0131 da devam etti.<\/p>\nAra\u015ft\u0131rmac\u0131lar, enfeksiyonun ilk d\u00f6neminde toplanan \u00f6rneklerden al\u0131nan genetik verileri ilerleyen aylarda al\u0131nan \u00f6rneklerle kar\u015f\u0131la\u015ft\u0131rd\u0131. Analizler vir\u00fcs su\u015funun de\u011fi\u015fmedi\u011fini g\u00f6sterdi. Ba\u015fka bir deyi\u015fle hasta yeniden enfekte olmam\u0131\u015ft\u0131, neredeyse bir y\u0131l boyunca ayn\u0131 vir\u00fcs\u00fc bar\u0131nd\u0131rmaya devam etmi\u015fti.<\/p>\n
Independent T\u00fcrk\u00e7e aktard\u0131\u011f\u0131 habere g\u00f6re hasta daha \u00f6nce lenfoma tedavisi g\u00f6rm\u00fc\u015ft\u00fc.<\/p>\n
Koronavir\u00fcs\u00fcn ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131flad\u0131\u011f\u0131 i\u00e7in hastan\u0131n v\u00fccudunda bu kadar uzun s\u00fcre kalabildi\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n
Hasta yakla\u015f\u0131k kanser nedeniyle \u00fc\u00e7 y\u0131l \u00f6nce CAR T h\u00fccre tedavisi g\u00f6rm\u00fc\u015ft\u00fc. Bu tedavide geneti\u011fiyle oynanan yapay T-h\u00fccre resept\u00f6rlerini ta\u015f\u0131yan h\u00fccreler hastalara uygulan\u0131yor.<\/p>\n
CAR T tedavisi bu hastada ba\u015far\u0131yla sonu\u00e7lanm\u0131\u015ft\u0131. Ancak v\u00fccutta antikor \u00fcreten B h\u00fccrelerinin \u00e7o\u011funu t\u00fcketerek ba\u011f\u0131\u015f\u0131kl\u0131k sistemini de zay\u0131flatm\u0131\u015ft\u0131.<\/p>\n
ABD\u2019de daha \u00f6nce bir l\u00f6semi hastas\u0131n\u0131n koronavir\u00fcs\u00fc 70 g\u00fcn boyunca bula\u015ft\u0131rabildi\u011fi vaka \u00f6rnekleri de kayda ge\u00e7mi\u015fti. Ancak bunun \u015fimdiye dek kayda ge\u00e7en en uzun vaka oldu\u011fu belirtiliyor.<\/p>\n
V\u0130R\u00dcS\u00dcN NASIL EVR\u0130LD\u0130\u011e\u0130 ANAL\u0130Z ED\u0130LEB\u0130L\u0130R<\/h2>\n
Hen\u00fcz hakem onay\u0131ndan ge\u00e7meyen ara\u015ft\u0131rman\u0131n yazar\u0131, molek\u00fcler virolog Elodie Ghedin, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin zay\u0131flad\u0131\u011f\u0131 hastalardaki koronavir\u00fcs enfeksiyonlar\u0131n genetik a\u00e7\u0131dan epey bilgi verdi\u011fini ifade etti.<\/p>\n
Ara\u015ft\u0131rmac\u0131lar, bu hastadan ve kronik enfeksiyondan mustarip di\u011fer vakalardan al\u0131nan \u00f6rnekleri analiz ederek vir\u00fcs\u00fcn nas\u0131l evrildi\u011fini analiz edebilir.<\/p>\n
Nitekim s\u00f6z konusu hastadan \u00f6rneklenen koronavir\u00fcste, iki genetik delesyon (genomun baz\u0131 par\u00e7alar\u0131n\u0131 silen mutasyonlar) tespit etti. \u00dcstelik bunlardan biri, vir\u00fcs\u00fcn h\u00fccreyi istila ederken kulland\u0131\u011f\u0131 sivri u\u00e7lu proteinini kodlayan genlerde meydana gelmi\u015fti.<\/p>\n
Kronik enfeksiyonlar nadir g\u00f6r\u00fclse de yeni varyantlar\u0131n ortaya \u00e7\u0131kmas\u0131na neden olabilir.<\/p>\n
Uzmanlara g\u00f6re vir\u00fcs\u00fcn zay\u0131f ba\u011f\u0131\u015f\u0131kl\u0131k sistemine sahip bir v\u00fccutta geli\u015fmek i\u00e7in daha fazla zaman ve alan bulma imkan\u0131 oluyor.<\/p>\n
Ghedin, bu t\u00fcr vakalar\u0131n “vir\u00fcs\u00fcn genetik alan\u0131 nas\u0131l ke\u015ffetti\u011finin g\u00f6r\u00fclmesi i\u00e7in bir pencere a\u00e7t\u0131\u011f\u0131n\u0131” ifade ediyor.<\/p>\n
Kaynak: Haber Global<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
ABD’de koronavir\u00fcse yakalanan bir kad\u0131n\u00a0 335 g\u00fcn pozitif kald\u0131 ve evde oksijen deste\u011fi almas\u0131na neden olan semptomlar\u0131 da devam etti….<\/p>\n","protected":false},"author":2,"featured_media":22387,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-22386","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"_links":{"self":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts\/22386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/comments?post=22386"}],"version-history":[{"count":0,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts\/22386\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/media\/22387"}],"wp:attachment":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/media?parent=22386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/categories?post=22386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/tags?post=22386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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