\n
Cambridge \u00dcniversitesi’nden ara\u015ft\u0131rmac\u0131lar, ‘insanlar\u0131n duygular\u0131 ve an\u0131lar\u0131n\u0131n de\u011fi\u015ftirilip de\u011fi\u015ftirilemeyece\u011fi ve silinip silinemeyece\u011fine i\u015faret edebilen bir protein ke\u015ffettiklerini’ duyurdu. Uzun s\u00fcreli an\u0131lar, iki kategoriye ayr\u0131l\u0131yor: isimler, yerler, olaylar gibi olgulara dayal\u0131 bellek ile duygular ve becerilere dayal\u0131 i\u00e7g\u00fcd\u00fcsel bellek.<\/p>\n
\u0130\u00e7g\u00fcd\u00fcsel an\u0131lar\u0131n d\u00f6n\u00fc\u015ft\u00fcr\u00fclebilece\u011fini d\u00fc\u015f\u00fcnen bilim insanlar\u0131na g\u00f6re b\u00f6yle bir \u00e7al\u0131\u015fma, travma sonras\u0131 stres bozuklu\u011fundan (TSSB) mustarip insanlara yard\u0131m edebilir.<\/p>\n
Sputnik T\u00fcrkiye’de yer alan habere g\u00f6re; Cambridge \u00dcniversitesi’nden ara\u015ft\u0131rmac\u0131lar, ke\u015ffettikleri ‘sap’ proteininin varl\u0131\u011f\u0131n\u0131n, \u00e7e\u015fitli n\u00f6ronlar aras\u0131ndaki ba\u011flant\u0131n\u0131n ne kadar g\u00fc\u00e7l\u00fc oldu\u011funu belirleyen resept\u00f6rler i\u00e7in destek g\u00f6revi g\u00f6rd\u00fc\u011f\u00fcn\u00fc ve bunun sonucunda beta resept\u00f6rler \u00fczerinde blokaj yapan propranolol kullan\u0131larak an\u0131lar\u0131n de\u011fi\u015ftirilip de\u011fi\u015ftirilemeyece\u011fi \u00fczerinde belirleyici olabilece\u011fini belirtti.<\/p>\n
Bilim insanlar\u0131, belle\u011fin \u00e7\u00f6kmesiyle do\u011frudan m\u0131 ilgili oldu\u011fu ya da daha derin bir reaksiyonun \u00fcr\u00fcn\u00fc m\u00fc oldu\u011funu netle\u015ftiremeseler de ‘sap’ proteinin g\u00fc\u00e7s\u00fczle\u015ftirilmesi halinde an\u0131lar\u0131n d\u00f6n\u00fc\u015ft\u00fcr\u00fclebilece\u011fi g\u00f6r\u00fc\u015f\u00fcnde. Ve ger\u00e7ekten \u00f6yleyse, me\u015fhur filmdeki gibi belli an\u0131lar\u0131 se\u00e7erek silmek yerine TSSB hastalar\u0131na yard\u0131m etmek i\u00e7in kullan\u0131lmas\u0131ndan yana.<\/p>\n
‘SAP PROTE\u0130N’<\/h2>\n
2004 y\u0131l\u0131nda New York’ta bir grup bilim insan\u0131, \u00f6\u011frenilmi\u015f travmay\u0131 unutmalar\u0131na yard\u0131mc\u0131 olmak i\u00e7in hayvanlar\u0131 propranolol ile tedavi etmi\u015fti, ancak bu sonucu yeniden elde edebilmek zor oldu.<\/p>\n
Bu yeni deneyde, \u0130van Pavlov’un k\u00f6pekleri ko\u015fulland\u0131rmas\u0131na benzer \u015fekilde, t\u0131klay\u0131c\u0131y\u0131 hafif bir elektrik \u00e7arpmas\u0131yla ili\u015fkilendirmek \u00fczere e\u011fitilen fareler, b\u00f6ylece t\u0131klay\u0131c\u0131y\u0131 korkuyla ili\u015fkilendirecekti. Farelere bu an\u0131 t\u0131klay\u0131c\u0131 ile hat\u0131rlat\u0131ld\u0131 ve hemen ard\u0131ndan propranolol uyguland\u0131.<\/p>\n
\u00d6nceki deneylerin aksine, farelerde bellek kayb\u0131 bildirilmedi. Bilim insanlar\u0131, ‘sap’ proteinin varl\u0131\u011f\u0131n\u0131 kullanarak bellekte istikrars\u0131zl\u0131k olmad\u0131\u011f\u0131 sonucuna vard\u0131.<\/p>\n
Ara\u015ft\u0131rmaya liderlik eden Dr. Amy Milton, “Bunlar ger\u00e7ekten karma\u015f\u0131k mekanizmalar ve \u00e7al\u0131\u015fman\u0131n hayvanlarla y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcn\u00fc akl\u0131m\u0131zda tutmam\u0131z laz\u0131m, zira insan beyni, hayvan beynine benzese de \u00e7ok daha karma\u015f\u0131kt\u0131r” ikaz\u0131nda bulunarak \u015funlar\u0131 s\u00f6yledi:<\/p>\n
“Bu \u00e7al\u0131\u015fman\u0131n, kahraman\u0131n hangi an\u0131lar\u0131 silece\u011fini se\u00e7ti\u011fi \u2018Eternal Sunshine of the Spotless Mind\u2019 gibi filmlerdeki durumlara g\u00f6t\u00fcrmesini beklemiyoruz. Ama hayvanlarda an\u0131lar\u0131 d\u00f6n\u00fc\u015ft\u00fcren etkenleri belirleyip tan\u0131mlamay\u0131 ve bunu insan hastalara terc\u00fcme etmeyi zamanla becerebilmeyi umuyoruz.<\/p>\n
Ancak biz bu m\u00fcdahaleden sonra daha \u00f6nce literat\u00fcre ge\u00e7en bellek kayb\u0131n\u0131 g\u00f6rmedik. Ard\u0131ndan ‘sap’ proteinin varl\u0131\u011f\u0131n\u0131 kulland\u0131k ki, ilk etapta an\u0131lar istikrars\u0131z hale gelmi\u015f mi, belirleyelim ve istikrars\u0131z hale gelmediklerini bulgulad\u0131k.”<\/p>\n
Dolay\u0131s\u0131yla ‘sap’ proteininin g\u00fc\u00e7s\u00fczle\u015fti\u011fi yerde, propranolol\u00fcn an\u0131lar\u0131 ortadan kald\u0131rmas\u0131n\u0131n m\u00fcmk\u00fcn olabilece\u011fi \u00f6ng\u00f6r\u00fcl\u00fcyor.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
T\u00fcrkiye’de ‘Sil Ba\u015ftan’ olarak \u00e7evrilen ‘Eternal Sunshine of the Spotless Mind’ filminin pop\u00fcler hale getirdi\u011fi istenmeyen an\u0131lar\u0131n silinebilmesine yard\u0131m edebilecek…<\/p>\n","protected":false},"author":2,"featured_media":20313,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-20312","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"_links":{"self":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts\/20312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/comments?post=20312"}],"version-history":[{"count":0,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/posts\/20312\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/media\/20313"}],"wp:attachment":[{"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/media?parent=20312"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/categories?post=20312"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/istanbulchannel.net\/index.php\/wp-json\/wp\/v2\/tags?post=20312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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